Lionel Messi and Copa America 2007

Messi played his first game in the 2007 Copa América on 29 June 2007, when Argentina defeated United States 4–1 in the first game. In this game, he showed his capabilities as a playmaker. He set up a goal for fellow striker Hernán Crespo and had numerous shots on target. Tevez came on as a substitute for Messi in the 79th minute and scored minutes later.

His second game was against Colombia, in which he won a penalty that Crespo converted to tie the game at 1–1. He also played a part in Argentina's second goal as he was fouled outside the box, which allowed Juan Roman Riquelme to score from a freekick, and increase Argentina's lead to 3–1. The final score of the game was 4–2 in Argentina's favor and guaranteed them a spot in the tournament's quarterfinals.

In the third game, against Paraguay the coach rested Messi having already qualified for the quarter-finals. He came off the bench in place of Esteban Cambiasso in the 64th minute, with the score at 0–0. In the 79th minute, he assisted a goal for Javier Mascherano. In the quarter-finals, as Argentina faced Peru, Messi scored the second goal of the game, from a Riquelme pass in a 4–0 win. During the semi-final match against Mexico, Messi scored a lob over Oswaldo Sánchez to see Argentina through to the final with a 3–0 win. Argentina went on to lose 3–0 to Brazil in the final. Messi was elected young player of the tournament.

Lionel Messi and World Cup 2006

The injury that kept Messi from playing for two months at the end of the 2005–06 season jeopardised his presence in the 2006 World Cup. Nevertheless, Messi was selected in the Argentina squad for the tournament on 15 May 2006. He also played in the final match before the World Cup against the Argentine U-20 team for 15 minutes and a friendly match against Angola from the 64th minute. He witnessed Argentina's opening match victory against Ivory Coast from the substitute's bench. In the next match against Serbia and Montenegro, Messi became the youngest player to represent Argentina at a World Cup when he came on as a substitute for Maxi Rodríguez in the 74th minute. He assisted Hernán Crespo's goal within minutes of entering the game and also scored the final goal in the 6–0 victory, making him the youngest scorer in the tournament and the sixth youngest goalscorer in the history of the World Cup. Messi started in Argentina's following 0–0 draw against the Netherlands. In the following game against Mexico, Messi came on as a substitute in the 84th minute, with the score tied at 1–1. He appeared to score a goal, but it was ruled offside with Argentina needing a late goal in extra time to proceed. Coach José Pekerman left Messi on the bench during the quarter-final match against Germany, which they lost 4–2 on a penalty shootout.